Dr. Glogauer is developing cutting-edge innovations and technologies in the dental field. He is a well respected and sought after clinician.
Bi-Weekly Audiocast: Conversations With Dr. Glogauer
Episode 7: HPV and Oral Cancer
The Checklist: Implenting Staging And Grading
Anna Louise Tolan, RDH, FADIA & Michael Glogauer, DDS, PhD, Dip. Peri
Sponsored by ODHA
This session focuses on how the comprehensive classification system allows clinicians to classify the patient/client, based on a system of staging and grading never before employed in periodontal diagnosis. Discussions will cover the principles behind the updated classification for periodontal diseases and how to integrate new staging and grading of periodontitis, indicating severity and extent of disease, lifetime disease experience and the client’s overall health status.
How the classification system is able to determine the best way to treat periodontitis and screen for disease recurrence will also be discussed. This lecture will provide clinicians with a clear understanding of CDHO expectations for using the classification system in their scope of practice and will build confidence for immediate chairside implementation of staging and grading.
- Understand the clinician’s role in adopting the improved classification system aimed at impacting client care.
- Recognize the clinical assessment skills needed for the classification of periodontal disease.
- Learn how the algorithm process was used to develop the staging and grading system.
- Utilize the checklist to classify clinical cases.
- Identify and classify periodontal disease using the staging and grading system.
Researchers at U of T Faculty of Dentistry Explore Rapid, Low-Cost COVID-19 Test
Researchers at U of T and local hospitals are looking to develop a mouth-based test for COVID-19 that would be quick and easy to administer to patients (photo by iStockphoto via Getty Images)
A simple mouth swab and rinse with testing technology adapted from a common viral detection method – the pap smear – could provide an easy, low cost and rapid diagnostic tool for COVID-19 infections, according to researchers at the University of Toronto.
Michael Glogauer, professor at the university’s Faculty of Dentistry and head of dental oncology at Princess Margaret Cancer Centre, is working with partners at Sunnybrook Health Sciences Centre, North York General Hospital, Sinai Health Systems and the University Health Network to research the viability of the platform.
The novel coronavirus that causes COVID-19 infections invades epithelial cells, such as those lining the lungs. But these epithelial cells are also prevalent in large numbers in the mouth, and especially on the tongue, where respiratory droplets are expelled. COVID-19 binds to the body’s epithelial cells through ACE-2 receptors – and, as Glogauer notes, “It just so happens that the tongue expresses extremely high levels of ACE-2 receptors.”
That makes the mouth, which is also one of the most easily accessible sites on the body – requiring no needles, and, unlike the nose, causing no pain when swabbed – an ideal place from which to cull samples.
“The tongue is a big net,” says Glogauer. “It will always be positive if an infection is present.”
Recently, Canada has launched a number of detection platforms to help with the fight against COVID-19. Some proposed detection methods require specialized technology or equipment. Others, like the common nasopharyngeal swab method, utilize certain chemicals for testing that are currently in short supply around the world.
But Glogauer says there’s a testing platform already in use which could make a significant difference in making COVID-19 testing more widely available: the pap smear.
“Pap smears show viral changes and inflammation in epithelial cells,” he says, adding that’s what technicians are on the hunt for with COVID-19.
The test is also routine and simple: epithelial cells are scraped, mounted onto slides, stained and viewed under a microscope. The cost? Approximately $30 per test.
Glogauer adds that laboratories across Canada could rapidly employ the platform.
“All labs are set up to do pap smears,” he says.
The process of adapting the test would be virtually painless, too. Samples could be easily collected by giving subjects an oral rinse and brushing their tongue. Results can be returned in a matter of hours. Importantly, the smear test could represent an easy ally for COVID-19 detection in developing nations, where lab technology is limited.
“If it works, it will be a real game changer for everyone,” Glogauer says.
While Glogauer cautions that the technology needs to be fine-tuned in order to prevent false positives, he says there’s significant potential to develop a fast and relatively inexpensive tool in the arsenal to find and detect COVID-19.
“Ideally, you want different testing modalities,” says Glogauer. “This could be one of them.”
Screening for Dental Infections Achieves 6-Fold Rduction in Dental Emergencies During Induction Chemotherapy for Acute Myeloid Leukemia
Clearing the Air: Managing Aerosols in Dentistry During COVID-19
- Neutrophil Diversity in Health and Disease
- Periodontal Health and Gingival Diseases and Conditions on an Intact and a Reduced Periodontium
- Identification of Neutrophil Surface Marker Changes in Health and Inflammation Using High-Throughput Screening Flow Cytometry